2020: Volume 2, Issue 1
Past Issues
Full-Text 
PDFTherapeutic Modalities in the Management of COVID-19: A Worldwide Landscape
Divya Bhat1, Venkatasruthi Surabathula2, Shivani Pandey3, Juhi Raju Uttamani4*, Nishreen Parekh5, Gabriela Fernandes6
1Nair dental college and hospital, Mumbai, Maharashtra, India
2Private dental practice, Mumbai, Maharashtra, India
3Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India
4Department of Periodontics, College of Dentistry, University of Illinois at Chicago, Chicago, IL, USA
5Manipal College of Dental Sciences, Manipal, Karnataka, India
6Department of Periodontics and Endodontics, Department of Oral Biology, SUNY Buffalo, Buffalo, NY, USA
*Corresponding Author: Dr. Juhi Raju Uttamani, University of Illinois at Chicago, College of Dentistry, Department of Periodontics, 461A, 801 South Paulina, Chicago, IL 60612, E-mail: [email protected]
Received: December 07, 2020
Published: December 31, 2020
ABSTRACT
Several strains of the novel Coronavirus have been identified and countries around the world are conducting research to identify, map and compare each type. Its infection can manifest with symptoms ranging from uncomplicated non-specific illness to a more damaging syndrome that include mild to moderate pneumonia (Covid-19 pneumonia broadly categorised into the phenotypes: L-type and H-type); Acute Respiratory Distress Syndrome; Sepsis and Septic shock. Although, this virus has a low mortality rate, the danger lies in its virulence and transmission dynamics. Until date, there has been no drug identified to be efficacious cure for this infection. Using the WHO (World Health Organization) guidelines as a base, various medical institutions are continuously updating their guidelines for the identification and therapeutic management of persons infected with Covid 19, with a strong emphasis on IPC measures. The guidelines also highlight detailed supportive treatment including supplemental oxygen therapy, ventilation, intubation and management of specific complications. The current treatment is tailored to patient centred management for the existing co-morbidities and appreciates a progress in the prognosis. The aim of this article is thus to review salient features of specific therapies being used now and summaries the different clinical trials being conducted so as to stay abreast of the possible treatment modalities.
KEYWORDS: COVID-19; Clinical trials; SARS COV-2; Therapeutic management
