Comprehensive Oral Rehabilitation of Mixed Dentition Affected by Amelogenesis Imperfecta: A Clinical Case Report

¹Assistant Professor, Pédiatric Dentistry, Dentistry Department Ibn El Jazzar University Hospital, Kairouan, Faculty of Dental Medicine of Monastir, Tunisia

²Professor in Pediatric Dentistry, Pediatric and Preventive Dentistry Department, Faculty of Dental Medicine of Monastir, Tunisia

³Laboratory of Biological, Clinical and Dento-Facial Approach, University of Monastir, Monastir, Tunisia

^*Correspondent author: Farah Chouchene, Assistant Professor, Pediatric Dentistry, Dentistry Department Ibn El Jazzar University Hospital, Kairouan, Faculty of Dental Medicine of Monastir, Tunisia, Email : [email protected]

Received: July 30, 2026

Published: August 24, 2026

Citation: Chouchene F, et al. (2026). Comprehensive Oral Rehabilitation of Mixed Dentition Affected by Amelogenesis Imperfecta: A Clinical Case Report. Dental. 8(1):24.

Copyright: Chouchene F, et al. © (2026).

ABSTRACT

Background: Amelogenesis imperfecta (AI) is a group of rare inherited enamel defects characterized by qualitative and/or quantitative abnormalities of enamel formation. Children with AI frequently experience tooth hypersensitivity, rapid enamel loss, compromised mastication, and esthetic concerns that may adversely affect their oral health-related quality of life.

Case Presentation: This report describes the multidisciplinary management of a 10-year-old girl with generalized amelogenesis imperfecta presenting with extensive enamel breakdown, yellow-brown discoloration, dentin exposure, severe hypersensitivity, and compromised esthetics. The clinical phenotype was considered predominantly hypocalcified based on the extensive post-eruptive enamel breakdown and qualitative enamel defects. The patient also presented with an Angle Class II Division 1 dental relationship, increased overjet, and anterior deep overbite. The treatment objectives were to preserve dental tissues, relieve hypersensitivity, restore masticatory function, improve esthetics, and optimize the developing occlusion.

Results: Immediate improvement in dental esthetics, elimination of hypersensitivity, restoration of masticatory efficiency, and increased patient satisfaction were achieved. At 18 months follow-up, the restorations remained clinically satisfactory, with good restoration integrity, maintained occlusal rehabilitation, and satisfactory oral hygiene.

Conclusion: Early multidisciplinary rehabilitation using conservative full-coverage restorations and individualized interceptive orthodontic management can provide effective functional and esthetic rehabilitation in children with AI during the mixed dentition stage. Regular long-term follow-up remains essential to monitor restoration durability, eruption, occlusal development, and the need for definitive treatment after completion of craniofacial growth.

Keywords: Amelogenesis Imperfect, Mixed Dentition, Oral Rehabilitation, Pediatric Dentistry, Case Report